As seasoned optometrists, we frequently receive inquiries regarding the efficacy of nutritional supplements in enhancing eye health or alleviating persistent symptoms. For a variety of eye-related issues, a well-balanced diet plays a supportive role. One area that has garnered substantial research evidence is dry eye disease, where both nutrition and targeted supplementation can yield significant improvements in symptoms.

Numerous clinical studies consistently demonstrate that a balanced diet, along with specific supplements, can enhance tear quality, diminish inflammation, and foster long-term comfort in the eyes. This compelling body of evidence underscores the importance of including supplements in a comprehensive management plan aimed at effectively addressing dry eye symptoms.
Two well-known supplements within this context are Lacritec and DRYeye Forte. While both products are designed to alleviate dry eye symptoms, they differ markedly in their formulations, potency, and the efficacy of their active ingredients within the body.
This comparative analysis delineates these differences, empowering you to make an informed choice regarding your approach to managing dry eye symptoms.
Detailed Ingredient Breakdown: Comparing Lacritec and DRYeye Forte
Key Ingredients Present in DRYeye Forte
- 667 mg re‑esterified omega‑3 triglycerides per capsule
- 240 mg EPA
- 160 mg DHA
- 455 mg borage oil providing 100 mg GLA
- Vitamin D3 200 IU
- Natural vitamin E 40 IU
Principal Ingredients in Lacritec
- 332 mg omega‑3 triglycerides per capsule
- 134 mg EPA
- 66.8 mg DHA
- 334 mg flaxseed oil
- Provides 192 mg ALA
- 434 mg borage oil supplying 95.5 mg GLA
- No vitamin D3
- No vitamin E


Understanding the Importance of Different Omega‑3 Fatty Acids
While both supplements contain omega‑3 fatty acids, it is essential to recognise that not all omega‑3s function identically within the body.
Lacritec contains flaxseed oil, which is a source of ALA. Although ALA is acknowledged as an omega‑3 fatty acid, the human body only converts a limited percentage of ALA into the more crucial forms necessary for alleviating dry eye symptoms, specifically EPA and DHA. Research indicates that the conversion rates of ALA to EPA are approximately 8–12 percent, with the majority of ALA being utilised as an energy source rather than for promoting eye health.
In contrast, DRYeye Forte provides EPA and DHA directly, using higher concentrations in a re‑esterified format. This innovative manufacturing technique enhances both absorption and bioavailability, ensuring that a more substantial portion of the active ingredients effectively reaches the tissues where they are most needed.
When comparing the effective levels of EPA and DHA:
- Three capsules of DRYeye Forte deliver a significantly higher amount of EPA and DHA compared to three capsules of Lacritec.
- To achieve the EPA and DHA content present in three capsules of DRYeye Forte, one would need to consume approximately six Lacritec capsules.
Both supplements recommend a starting dosage of three capsules daily during the treatment phase, making this difference clinically significant for users in search of effective relief.


Assessing the Quality and Sources of Fish Oil Used in Supplements
Both Lacritec and DRYeye Forte are produced in Australia and utilise high-quality fish oils sourced from small, cold-water fish such as sardines and anchovies from Peru. Smaller fish typically accumulate fewer toxins, making them a safer option for supplementation. Both oils undergo stringent purification and deodorisation processes to eliminate impurities and reduce any unpleasant fishy aftertaste.
DRYeye Forte incorporates re‑esterified triglyceride fish oil, which has been shown to offer superior absorption compared to traditional ethyl ester forms. This advancement not only enhances consistency but also minimises gastrointestinal discomfort for many users, making it a preferred option.
The Importance of Vitamin D and Vitamin E for Enhancing Eye Health
A significant distinction between the two supplements is that DRYeye Forte includes both vitamin D3 and natural vitamin E in its formulation, which can profoundly impact eye health.
The Beneficial Effects of Vitamin D3 on Eye Health
Research demonstrates a strong association between low vitamin D levels and dry eye symptoms. Studies suggest that vitamin D may:
- Reduce ocular inflammation
- Enhance tear stability
- Facilitate healing of the ocular surface
- Alleviate light sensitivity and overall ocular discomfort
The Comprehensive Benefits of Vitamin E
Vitamin E serves a crucial dual purpose. It not only offers antioxidant and anti-inflammatory properties but also protects omega‑3 fatty acids from oxidative damage. Prolonged fish oil supplementation can increase the body's demand for vitamin E, making its presence essential for maintaining balance and optimising omega‑3 metabolism.
Conversely, Lacritec does not contain either vitamin D3 or vitamin E, which may limit its overall effectiveness in supporting eye health.
Considering the Safety and Tolerability of Eye Health Supplements
Both supplements are generally well tolerated when taken according to the recommended dosage.
Potential side effects from either product may include mild gastrointestinal issues such as reflux, bloating, or loose stools. These effects are usually dose-dependent and can vary among individuals.
Individuals on blood-thinning medications or those with bleeding disorders should consult a healthcare professional prior to starting either supplement.
Due to the presence of vitamin D3 in DRYeye Forte, individuals with hypercalcemia, kidney disease, or conditions that are sensitive to vitamin D should seek medical advice before use. In such instances, Lacritec may be a more suitable alternative owing to its lack of vitamin D.
As with all supplements, consulting a healthcare provider is advisable if you are pregnant, breastfeeding, or managing chronic health conditions.
Selecting the Most Suitable Supplement to Address Your Needs
For the majority of individuals suffering from moderate to severe dry eye disease, DRYeye Forte offers more comprehensive and targeted support. This is attributed to:
- Higher concentrations of effective EPA and DHA
- Enhanced absorption through the use of re‑esterified fish oil
- Inclusion of vitamin D3 and vitamin E, which assist in controlling inflammation and supporting tear production
Lacritec may still be appropriate for those experiencing very mild symptoms or for individuals who cannot tolerate vitamin D supplementation.

Vital Insights and Recommendations for Managing Dry Eye Symptoms
Both supplements can make a positive contribution to managing dry eye symptoms; however, they are not interchangeable.
DRYeye Forte provides higher therapeutic dosages of the most effective omega‑3 fatty acids, along with additional nutrients that assist in managing inflammation, enhancing tear quality, and supporting the health of the ocular surface. For many patients, this translates to more effective symptom relief with fewer capsules required on a daily basis.
Ultimately, the best supplement is one that fits seamlessly into a personalised dry eye treatment plan. If you are uncertain about which product is best suited for your needs, we recommend consulting with your optometrist or healthcare provider for tailored guidance.
Lacritec vs DRYeye Forte Most Commonly Asked Questions
Which supplement is more effective for relieving dry eye symptoms: Lacritec or DRYeye Forte?
For the majority of individuals experiencing moderate to severe dry eye symptoms, DRYeye Forte emerges as the more effective choice. It contains higher levels of EPA and DHA, the active omega-3s known to reduce inflammation and enhance tear quality, alongside vitamin D3 and vitamin E for additional support. Lacritec may still be advantageous in milder cases or when vitamin D supplementation is not recommended.
What are the primary distinctions between Lacritec and DRYeye Forte?
The major distinction lies in their formulations and potency. DRYeye Forte contains highly bioavailable re-esterified fish oils that deliver clinically significant doses of EPA and DHA, complemented by vitamin D3 and natural vitamin E. In contrast, Lacritec utilises flaxseed oil, which provides ALA — an omega-3 source that is less efficient and has limited conversion into EPA and DHA.
How many Lacritec capsules correspond to the EPA/DHA dosage found in DRYeye Forte?
To obtain the same levels of EPA and DHA present in three capsules of DRYeye Forte, one would need to take approximately six Lacritec capsules. This is due to Lacritec's lower omega-3 concentration and its dependence on ALA, which only partially converts into the more bioactive forms required by the body.
Is it safe to take DRYeye Forte if I have kidney disease or elevated calcium levels?
If you have kidney disease or hypercalcemia, it is crucial to consult your healthcare provider prior to starting DRYeye Forte. The presence of vitamin D3 may not be suitable for individuals with these conditions. In such scenarios, Lacritec, which does not contain vitamin D, may be a more fitting alternative.
Will I need to take dry eye supplements indefinitely?
Not necessarily. Many individuals commence treatment with a higher dosage (three capsules daily) for 6–8 weeks and then reassess their condition with their optometrist. Some may transition to a maintenance dosage or discontinue use altogether if their symptoms improve. However, ongoing supplementation may be beneficial for chronic or seasonal dry eye, particularly if there are underlying issues like inflammation or oil gland dysfunction.
Lacritec vs DRYeye Forte: Which Supplement Is the Better Choice for Dry Eye Relief?
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